Crestor Legal Claims
Crestor (rosuvastatin calcium) is a medication prescribed along with a healthy diet for lowering cholesterol. According to manufacturer AstraZeneca, Crestor has received regulatory approval in over 95 countries. Nearly 15 million patients have been prescribed Crestor worldwide.
Unfortunately, troubling and potentially life-threatening side effects have also been reported by Crestor users. Crestor belongs to the class of drugs called statins that are often prescribed to lower harmful cholesterol levels. Other statin drugs include Mevacor, Pravacor, Zocor, and Lipitor. But Crestor is currently regarded as the most powerful statin drug on the market.
In addition to their effects on cholesterol, statins have other beneficial effects. The most important may be their ability to reduce inflammation, and in particular C-reactive protein (CRP), which is elevated in people who are at a higher risk of having heart attacks. The American Heart Association recommends, “Statin should be the first drug used by most people to control cholesterol,” although it doesn’t recommend Crestor as a first choice.
Learn About Who Can Sue For Crestor Claims
Crestor is marketed by AstraZeneca, a major international healthcare business and one of the top five pharmaceutical companies in the world – with healthcare sales of over $18.8 billion ($8.7 billion in the United States alone). Crestor was developed by Shionogi & Co., a Japanese pharmaceutical manufacturer. Shionogi receives royalty payments from AstraZeneca on all Crestor sales outside Japan. Inside Japan, the companies jointly market the cholesterol drug.
Crestor was approved by the U.S. Food and Drug Administration (FDA) in late 2003. Almost immediately, reports appeared that patients taking approved doses of the drug had developed kidney failure or muscle damage. At least one patient died of kidney failure and rhabdomyolysis.
Rhabdomyolysis, a rare but deadly muscle disorder, is the rapid breakdown of skeletal muscle tissue, which sends massive amounts of muscle proteins into the bloodstream. The muscle proteins become trapped in the kidneys, leading to potentially fatal kidney damage and even kidney failure.
Crestor has more recently been linked to other troubling side effects, including Stevens–Johnson syndrome (SJS), a rare but potentially life threatening condition characterized by extreme skin sensitivity. SJS can be caused by trauma or medication.
In spite of such questions about the safety of Crestor, AstraZeneca continues to aggressively market the drug, and physicians continue to prescribe it.
In 2005 the online journal of the American Heart Association published an article suggesting that Crestor is more likely to cause side effects, such as muscle and liver damage than other cholesterol medicines.
Some researchers are unconvinced about the efficacy of statins, and apparently the drug company is too. Although AstraZeneca aggressively markets Crestor as a cholesterol lowering drug, its own current print advertising carries the disclaimer, “Crestor has not been determined to prevent heart disease, heart attacks or strokes.”
What Crestor does do is act on other parts of the body as well, in potentially dangerous ways. AstraZeneca advises, “Any unexplained muscle pain or weakness could be a sign of a rare but serious side effect and should be reported to your doctor right away.” That “rare but serious” side effect would be the sometimes fatal rhabdomyolysis.
Crestor’s 2005 revised labeling notes that Asian American patients may be at greater risk than the general population for muscle injury due to Crestor. The “Dosage and Administration” section of the Crestor label now states that the 5 mg dose of Crestor should be considered as the start dose for Asian American patients (the recommended start for other patients is 20 mg, which can go as high as 40 mg.)
If you or someone in your family has experienced a serious reaction to Crestor you should immediately discuss it with your physician. You can also report your Crestor side effects to MedWatch, the FDA’s Safety Information and Adverse Event Reporting Program.
MedWatch allows healthcare professionals and consumers to report serious problems that they suspect are associated with a prescription drug. Health care providers are not required to report adverse reactions to the FDA. If your health care provider chooses not to report your reaction, you can report it yourself online, or by phone, mail, or fax.
Because the statute of limitations may apply, you need to act now if you have been injured by Crestor. If you have experienced negative side effects from Crestor use, contact a pharmaceutical attorney
Read More About The Risks Associated With Crestor